What medicine should be taken for nephritis and high blood pressure?
In recent years, the number of patients with nephritis combined with hypertension has gradually increased, and how to use medications rationally has become the focus of many people's attention. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with a detailed analysis of drug treatment options for nephritis and hypertension, and provide structured data for reference.
1. Pathogenesis of nephritis and hypertension
Nephritis hypertension is an increase in blood pressure caused by factors such as impaired kidney function, water and sodium retention, and activation of the renin-angiotensin system (RAS). If not controlled in time, it may further aggravate kidney damage and form a vicious cycle.
2. Commonly used drugs for nephritis and hypertension
According to clinical guidelines and expert consensus, drug treatment for nephritis and hypertension mainly includes the following categories:
| drug class | Representative medicine | Mechanism of action | Applicable people |
|---|---|---|---|
| ACEI (angiotensin-converting enzyme inhibitor) | benazepril, fosinopril | Inhibit the RAS system and reduce proteinuria | Nephritis patients with proteinuria |
| ARB (angiotensin II receptor blocker) | Valsartan, Losartan | Block angiotensin II receptors and protect kidneys | Patients who are intolerant to ACE inhibitors |
| CCB (calcium channel blocker) | Amlodipine, nifedipine | Dilate blood vessels and lower blood pressure | Elderly patients or those with arteriosclerosis |
| diuretics | Hydrochlorothiazide, furosemide | Reduce water and sodium retention and reduce blood volume | Patients with obvious edema |
3. Precautions for drug selection
1.ACEI/ARB is the first choice: This type of drug can not only lower blood pressure, but also reduce proteinuria and delay the deterioration of renal function, but blood potassium and renal function need to be monitored. 2.Avoid nephrotoxic drugs: Non-steroidal anti-inflammatory drugs (NSAIDs) may increase the burden on the kidneys and should be used with caution. 3.personalized medicine: Adjust the type and dosage of drugs according to the patient's age and complications (such as diabetes, heart failure).
4. Answers to recent hot questions
Combined with the search hot spots on the entire network in the past 10 days, the following issues have attracted much attention:
| Popular questions | Professional answers |
|---|---|
| Can patients with nephritis and high blood pressure take ACEI for a long time? | Yes, but serum potassium and creatinine need to be reviewed regularly. If side effects occur, ARB can be used. |
| What should I do if my blood pressure is not well controlled? | CCB or diuretics can be combined, and lifestyle adjustments (such as low-salt diet) can be made if necessary. |
| Can Chinese medicine replace Western medicine? | Some Chinese medicines (such as astragalus) may assist in lowering blood pressure, but they cannot completely replace Western medicines. |
5. Life conditioning suggestions
In addition to drug treatment, lifestyle adjustments are equally important: 1.low salt diet: Daily salt intake should not exceed 5g. 2.Control protein intake: Appropriate amount of high-quality protein (such as eggs, lean meat) to avoid increasing the burden on the kidneys. 3.regular exercise: Such as walking, Tai Chi, and avoid strenuous exercise.
Summarize
Drug treatment of nephritis and hypertension needs to focus on protecting renal function. ACEI/ARB is the first choice, but the plan needs to be adjusted based on the patient's specific conditions. Recent hot topics also remind patients to pay attention to drug side effects and the importance of combination therapy. It is recommended to standardize medication under the guidance of a doctor and cooperate with a healthy lifestyle to achieve the best therapeutic effect.
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